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Intra‐epidermal carcinoma of the eyelid margin
Author(s) -
McCALLUM D.I.,
KINMONT P.D.C.,
WILLIAMS D.WYNN,
COTTON R.E.,
WROUGHTON M.A.
Publication year - 1975
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1975.tb06489.x
Subject(s) - eyelid , margin (machine learning) , carcinoma , medicine , dermatology , surgery , pathology , computer science , machine learning
SUMMARY Twenty‐two cases of intra‐epidermal carcinoma of the ciliary margin have been diagnosed in a 15‐year survey. The clinical appearance is variable, resembling in some instances a benign warty lesion, and in others a fully developed squamous cell carcinoma. As the lesion grows it produces keratotic plugging of the lash follicles and nodules on the lid margin; in due course this results in loss of the related cilia. When dermal invasion occurs the resultant squamous cell carcinoma is potentially dangerous because of the involvement of the adnexal structures, which on the ciliary margins are particularly large and penetrate deeply into the lid substance. Adequate biopsy which includes at least one lash follicle is essential for accurate diagnosis, and treatment requires complete excision with a reasonable margin for safety. Of the twenty‐two patients, nineteen were male and three female; fourteen of the men involved had handled oils and greases for prolonged periods.