Premium
The percutaneous penetration of nandrolone decanoate *
Author(s) -
FOREMAN M.I.,
CLANACHAN I.
Publication year - 1975
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1975.tb06475.x
Subject(s) - percutaneous , penetration (warfare) , nandrolone , medicine , surgery , engineering , operations research , anabolism
SUMMARY A Study has been carried out of the penetration of nandrolone decanoate through human cadaver skin in vitro using radioactive tracer material. The radiochemical purity of the material desorbed from the dermal skin surface is very much less than that of the material absorbed into the epidermal surface. These observations are a consequence of the low level of overall penetration of the skin by the steroid. There is also a possibility that a small percentage of the steroid is being metabolized by micro‐organisms present in the skin samples.