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Repeated tissue sampling with a dental broach A TRIAL IN CUTANEOUS LEISHMANIASIS
Author(s) -
GRIFFITHS W.A.D.,
DUTZ W.
Publication year - 1975
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1975.tb06474.x
Subject(s) - leishmaniasis , cutaneous leishmaniasis , medicine , sampling (signal processing) , dermatology , lesion , leprosy , leishmania , pathology , parasite hosting , computer science , filter (signal processing) , world wide web , computer vision
SUMMARY A simple and almost painless technique for repeated sampling of dermal infiltrates with a dendritic broach was used in the diagnosis of cutaneous leishmaniasis. This technique can be used to advantage to obtain organisms and cells underneath crusted lesions and to evaluate not only the number of organisms but also the cell pattern at different depths of the lesion. It can be used repeatedly on the same lesions without appreciably disturbing the natural progress of the disease and is therefore well suited to monitor the in vivo effects of therapeutic agents on organisms. Its use in twenty‐one cases of cutaneous leishmaniasis and one case of cutaneous leprosy is described.