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The lichen planus‐like eruption after bone marrow transplantation
Author(s) -
SAURAT J.H.,
GLUCKMAN ELIANE,
BUSSEL ANETTE,
DIDIERJEAN LILIANE,
PUISSANT A.
Publication year - 1975
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1975.tb05118.x
Subject(s) - saint , bone marrow transplantation , medicine , transplantation , classics , art history , dermatology , art , surgery
SUMMARY A lichen planus‐like eruption was seen in four patients after bone marrow transplantation. The skin and mucous membrane appearance closely mimicked lichen planus. The histopathology was also very similar to lichen planus. The occurrence of a lichen planus‐like eruption (LPLE) after an immune basal cell damage related to the graft‐versus‐host reaction raised the question of the immune nature of this eruption. The correlation found between biological signs of graft‐versus‐host reaction and the outbreak or relapse of the lichen planus‐like eruption supports the hypothesis that the skin changes could be a sign of a chronic immune response against recipient epidermis.