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Oral retinoic acid as therapy for congenital ichthyosiform erythroderma
Author(s) -
ERIKSEN L.,
CORMANE R.H.
Publication year - 1975
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1975.tb03086.x
Subject(s) - erythroderma , medicine , dermatology , ichthyosis , retinoic acid , lamellar ichthyosis , keratolytic , hyperkeratosis , tretinoin , biology , genetics , gene
SUMMARY Oral retinoic acid has been therapeutically beneficial for three patients with congenital ichthyosiform erythroderma and one with congenital bullous ichthyosiform erythroderma. Response to therapy was slow but definite with suppression of scale formation, marked reduction of painful cracking of the underlying epidermis and disappearance of skin irritation. Side effects have not occurred. Therapy had to be maintained to prevent recurrence of symptoms.