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A follow‐up of tetracycline‐treated rosacea
Author(s) -
KNIGHT ARTHUR G.,
VICKERS C.F.H.
Publication year - 1975
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1975.tb02252.x
Subject(s) - rosacea , clearance , tetracycline , medicine , dermatology , keratitis , drug , surgery , antibiotics , pharmacology , biology , microbiology and biotechnology , acne , urology
SUMMARY Seventy patients with rosacea were treated with systemic tetracycline for 6 months. Sixty‐eight of them cleared with treatment. After withdrawal of the drug seventeen relapsed immediately and the overall relapse rate over 4 years was 69%. The serum tetracycline levels were not significantly different in two patients who failed to respond. Six patients had rosacea keratitis and responded dramatically within I month. Symptoms recurred as the drug was withdrawn. It is suggested that rosacea patients with keratitis should receive early and prolonged tetracycline medication.