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Double blind controlled study of treatment of atopic eczema with a preparation of hydrocortisone in a new drug delivery system versus betamethasone 17‐valerate
Author(s) -
ALMEYDA JOHN,
BURT B. W.
Publication year - 1974
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1974.tb12948.x
Subject(s) - betamethasone , medicine , dermatology , corticosteroid , double blind , drug , hydrocortisone , pharmacology , pathology , placebo , alternative medicine
SUMMARY A double blind study has shown that topical treatment with a new preparation of I% hydrocortisone in a stabilized carbamide drug delivery system effectively controls atopic eczema without the hazards of potent fluorinated corticosteroids. Clinical evaluation confirms that it is at least as effective as 0·1% betamethasone 17‐valerate. The preparation has the physical properties of both a cream and an ointment and can be used in place of either. It has a high level of patient acceptance and can be used in fissured eczemas without causing any sensations of stinging or smarting.