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Elution of antibodies from the lymphocyte membrane in certain dermatoses
Author(s) -
CORMANE R. H.,
HAMERLINCK F.,
HUSZ S.
Publication year - 1974
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1974.tb12901.x
Subject(s) - dermatology , medicine , library science , history , computer science
SUMMARY The lymphocyte eluates of three patients with discoid lupus erythematosus and two patients with pemphigoid possessed basement membrane antibody of the IgG class either for normal human skin or guinea‐pig lip. The lymphocyte eluates from one patient with pemphigus did contain antibody (IgG) reactive with the intercellular substances of monkey oesophagus, and that of a patient with a drug reaction showed antibody reactive with basal cells of stratified epithehum. These results indicate either antibody synthesis by the lymphocytes themselves, or that these cells may provide antigenic receptors reactive with specific antibody.