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The pathogenic status of yeasts infecting ulcerated legs
Author(s) -
SMITH R. J.,
ENGLISH M. P.,
WARIN R. P.
Publication year - 1974
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1974.tb12456.x
Subject(s) - medicine , dermatology , family medicine , library science , computer science
SUMMARY Seventeen patients with common venous ulcers, from which Candida species were isolated, were treated with nystatin incorporated into an ointment applied once per week before the application of compressive bandages. In half the patients the regime was used for 1 month, followed by a month with the same treatment but without nystatin; this procedure was reversed in the remainder of the patients. Regular mycological examination showed that the yeast was eradicated in all the cases when nystatin was used, but the clinical response was not closely related to the disappearance of the yeast. Sixteen patients were then followed up for a year, or until the ulcers had healed, and were treated with nystatin for as long as the yeast was shown to be present. This treatment did not have any obvious clinical effect on the rate of healing.