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Azathioprine in the treatment of muco‐cutaneous pemphigoid
Author(s) -
DAVE VINAY K.,
VICKERS C. F. H.
Publication year - 1974
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1974.tb06383.x
Subject(s) - azathioprine , medicine , pemphigoid , concomitant , dermatology , surgery , bullous pemphigoid , pathology , immunology , disease , antibody
Four patients with muco‐cutaneous pemphigoid were treated with azathioprine. Satisfactory control of the cutaneous lesions was maintained in two patients, in one of them with concomitant use of a corticesteroid. Oral ulceration was less frequent in three patients, and in two patients with ocular involvement visual impairment did not progress. Although the various complications of azathioprine therapy need to be considered, this drug may significantly improve the prognosis regarding vision in patients with ocular changes otherwise totally unresponsive to therapy.