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Enzymes of buccal epithelium in psoriasis
Author(s) -
HAMMAR HANS
Publication year - 1973
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1973.tb07588.x
Subject(s) - epithelium , enzyme , psoriasis , basal (medicine) , buccal administration , chemistry , biology , medicine , pathology , biochemistry , dermatology , dentistry , insulin
summary The normal buccal mucosa was analysed by application of Lowry's microtechniques in thirteen psoriatic patients with guttate skin lesions and in fifteen healthy controls, for the following enzymes: glucose 6‐phosphate, glycerol 3‐phosphate and glyceraldchydc phosphate dehydrogenases, pyruvate kinase (PK) and NAD and NADP dependent isocitrate dehydrogenases. The material was obtained from superficial and adjacent basal parts of the epithelial rete ridges. Enzymatic activities were higher in basal than in superficial epithelium except for PK in controls. The PK activity was lower in the psoriatic patients than in the controls when the superficial epithelium was compared. No differences were found between the controls and the psoriatic patients with regard to activities of the other five enzymes measured.