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The uninvolved psoriatic epidermis
Author(s) -
JARRETT A.
Publication year - 1973
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1973.tb07586.x
Subject(s) - epidermis (zoology) , dehydrogenase , acid phosphatase , psoriasis , chemistry , enzyme , biology , dermatology , endocrinology , biochemistry , medicine , anatomy
summary Normal control and apparently unaffected skin from psoriatics have been compared quantitatively for their acid phosphatase activity. The unaffected skin from psoriatics shows a more rapid reaction, which may be related to a lysosomal defect. No marked differences were detected in the dehydrogenase reactions in these two tissues. However, in frankly involved psoriatic skin it has previously been shown that there is a marked increase in glucose‐6‐phosphate dehydrogenase activity in the transitional zone. In the present report an increase in glycero‐phosphate dehydrogenase activity has been demonstrated in the lower portion of psoriatic epidermis.