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Neutron activation analysis of trace elements in skin
Author(s) -
MOLOKHIA MOHAMED M.,
PORTNOY BENJAMIN
Publication year - 1973
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1973.tb07564.x
Subject(s) - vitiligo , zinc , copper , dermatology , medicine , lesion , chemistry , pathology , organic chemistry
SUMMARY Copper and zinc levels were estimated in serum and skin of nineteen vitiligo patients as well as in pigmented moles, seborrhoeic warts and normal skin. In seborrhoeic warts, high zinc levels were associated with excessive melanization and an abundance of ATPase+ve dendritic cells. Zinc levels were also significantly increased in pigmented moles compared with those in normal surrounding skin. In vitiligo, there was a significant reduction in serum zinc while copper levels were increased in the hyperpigmented zone surrounding the lesion. The results of copper analysis in vitiligo neither support a deficiency role for copper nor justify its use in the treatment of that disease.