Premium
Induction of epithelial hyperplasia by Candida albicans
Author(s) -
CAWSON R.A.
Publication year - 1973
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1973.tb03011.x
Subject(s) - candida albicans , microbiology and biotechnology , hyperplasia , medicine , biology , pathology
SUMMARY Epithelial hyperplasia is a characteristic feature of mucosal infection by Candida albicans , but doubt may exist as to the extent to which this reaction is a direct result of fungal invasion. An experimental model using the chick embryo chorio‐allantoic membrane infected by C. albicans shows an essentially similar hyperplastic response of the ectoderm, and several features in common with human infections. It is suggested that the intracellular growth of C. albicans in epithelium is probably a major factor provoking this response.