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Evaluation of skin damage. I
Author(s) -
THIELE F.A.J.,
MALTEN K.E.
Publication year - 1973
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1973.tb02992.x
Subject(s) - sodium hydroxide , sodium , chemistry , human skin , phosphate , alkali metal , chromatography , biochemistry , biology , organic chemistry , genetics
SUMMARY The impedance of human skin was measured at a frequency of 25 Hz and 0.032 mA before, during and after exposing 6 cm 2 skin for 60–240 min to 10 or 12 ml of alkali (NaOH and sodium phosphate) and sodium chloride solutions, adjusted to different pHs. From the impedance and phase angle values, measured at intervals of 10–60 min between different pairs of skin sites, the changes in the single transition resistances of these skin sites were calculated. Sodium hydroxide (NaOH) solution at pH 12.0, within 10 to 15 min, abolished skin resistance completely; a solution of sodium phosphate, adjusted to the same pH, affected skin resistance similarly, but only after 60 minutes. The order of severity in skin effects of solutions of other alkaline substances, adjusted to different pHs was determined.