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FAMILIAL LICHEN AMYLOIDOSIS
Author(s) -
RAJAGOPALAN K.,
TAY C. H.
Publication year - 1972
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1972.tb16186.x
Subject(s) - general hospital , medicine , family medicine , unit (ring theory) , dermatology , library science , general surgery , psychology , mathematics education , computer science
Summary.— Nineteen members in 4 successive generations of one Chinese family in Malaysia were found to have classical lichen amyloidosis without systemic amyloid involvement. The disease was transmitted as an autosomal dominant trait with variable penetrance. Sex ratio was equal and the onset was around the age of puberty. The extent and severity of the lesions tended to increase with age. No patient subsequently developed the systemic form of amyloidosis. The present findings further strengthen the genetic theory of lichen amyloidosis.