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LICHEN PLANUS; AN INBOEN ERROR OF METABOLISM
Author(s) -
COTTON D. W. K.,
HURK JOSÉ J. M. A.,
STAAK W. B. J. M.
Publication year - 1972
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1972.tb07420.x
Subject(s) - dehydrogenase , etiology , glucose 6 phosphate dehydrogenase , lichen , enzyme , dermatology , substrate (aquarium) , metabolism , phosphate , medicine , biology , chemistry , biochemistry , botany , ecology
Summary.— The Km of the enzyme glucose‐6‐phosphate dehydrogenase for its substrate glucose‐6‐phosphate has been determined in normal human skin and skin from lichen planus patients. There was a clear difference between the 2 groups comparable to that found in congenital erythrocyte glucose‐6‐phosphate dehydrogenase deficiency. The results are discussed in relation to the aetiology and clinical picture of lichen planus.