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FURTHER EXPERIENCES OF TOXIC EPIDERMAL NECROLYSIS INCRIMINATING ALLOPURINOL, PYRAZOLONE AND DERIVATIVES
Author(s) -
STRATIGOS J. D.,
BARTSOKAS St.K.,
CAPETANAKIS J.
Publication year - 1972
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1972.tb05070.x
Subject(s) - toxic epidermal necrolysis , allopurinol , dermatology , medicine , erythroderma , exanthem , skin biopsy , biopsy , pathology
Summary.— Four cases of toxic epidermal necrolysis, confirmed by skin biopsy, are described. The first case was due to allopurinol. The second case was caused by a pyrazolone derivative in a patient who, 15 days previously, had developed an urticarial exanthem from tetanus antitoxin. In these 2 fatal cases Stevens–Johnson syndrome coexisted. In the remaining cases toxic epidermal necrolysis occurred alone and recovery was uneventful.