Premium
THE CONTROL OF GLYCOGEN UTILIZATION IN SKIN; PHOSPHORYLASE B KINASE AND PHOSPHORYLASE A PHOSPHATASE
Author(s) -
MIER P. D.,
SUTORIUS A. H. M.
Publication year - 1972
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1972.tb01890.x
Subject(s) - glycogen phosphorylase , phosphorylase kinase , phosphatase , glycogen synthase , biochemistry , medicine , glycogen , enzyme , chemistry
SUMMARY.— The activation of phosphorylase b and the inactivation of phos‐phorylase a by skin homogenates have both been demonstrated for the first time. Certain properties of the enzymes catalysing these reactions (phosphorylase b kinase and phosphorylase a phosphatase, respectively) were investigated; it was concluded that the control system in skin is similar to that of muscle and liver. The possibility of certain dermatoses being associated with defects in this system is discussed.