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EXPERIMENTAL ZOSTERIFORM HERPES SIMPLEX VIRUS INFECTION IN MOUSE SKIN
Author(s) -
ROBINSON T. W. E.,
DOVER J. R.
Publication year - 1972
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1972.tb01889.x
Subject(s) - herpes simplex virus , virology , virus , incidence (geometry) , paralysis , strain (injury) , medicine , biology , surgery , physics , optics
SUMMARY.— A highly reproducible model in which linear zosteriform lesions are produced in the skin of Webster Schneider mice, using an oral strain of herpes simplex virus, (HSV) is described. The incidence of infection is high, and a large proportion of infected animals develop a highly characteristic ascending paralysis which is invariably fatal.