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EFFECTS OF PROPRANOLOL ON THE RESPONSE OF HUMAN ECCRINE SWEAT GLANDS TO ACETYLCHOLINE
Author(s) -
FOSTER K. G.,
HASPINEALL J. R.,
MOLLEL C. L.
Publication year - 1971
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1971.tb14031.x
Subject(s) - propranolol , sweat , acetylcholine , sweat gland , endocrinology , medicine , cholinergic , eccrine sweat , eccrine sweat gland , secretion , chemistry
Summary.— Propranolol had no marked effects on the acetylcholine‐induced sweat response in normal subjects. The only effects were (1) a slight and transient prolongation of the secretion; (2) a very slight and transient anti‐cholinergic activity. These findings do not support the existence of a β‐receptor inhibitory mechanism affecting sweat gland activity as postulated by Hemels (1970).