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A STIMULANT TO DNA SYNTHESIS IN GUINEA‐PIG EAR EPIDERMIS
Author(s) -
HELL ELIZABETH
Publication year - 1970
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1970.tb15757.x
Subject(s) - stimulant , epidermis (zoology) , guinea pig , dna synthesis , in vitro , dna , pharmacology , microbiology and biotechnology , biology , chemistry , medicine , anatomy , biochemistry , genetics
SUMMARY.– Experiments reported in this paper show that grinding up skin in tissue culture medium can release a potent stimulant to epidermal cells, causing them to go into DNA synthesis within 4 hr. in vitro. Some progress has been made in elucidating the nature of this stimulant, but it is not yet characterized. A possible role in wound healing is discussed.