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AUTOANTIBODIES IN DERMATITIS HERPETIFORMIS
Author(s) -
FRASER N. G.
Publication year - 1970
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1970.tb15754.x
Subject(s) - dermatitis herpetiformis , medicine , autoantibody , thyroglobulin , incidence (geometry) , dermatology , antibody , etiology , anti thyroid autoantibodies , immunology , gastroenterology , disease , physics , optics
SUMMARY.– The incidence of thyroid and gastric autoantibodies in the sera of 43 patients with dermatitis herpetiformis was determined and compared with the incidence in a control group matched for age and sex. Thyroid microsomal antibody was present in the sera of 9 patients in the dermatitis herpetiformis group compared with 1 patient in the control group. This difference is statistically significant. Thyroglobulin antibody was present in the sera of 6 patients in the dermatitis herpetiformis group. It was not present in the control group. The incidence of gastric parietal cell antibody was increased, but not to a statistically significant extent, in the dermatitis herpetiformis patients. The relevance of these findings to the aetiology of dermatitis herpetiformis is discussed.