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PACHVONVCHIA
Author(s) -
ACHTEN G.,
WANETROUARD J.
Publication year - 1970
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1970.tb15026.x
Subject(s) - medicine , dermatology
SUMMARY.— One hundred and two cases of pachyonychia with onycholysis were studied both histologically and histochemically on transverse sections of the extremities of the nail. Globular structures were found in the ventral nail formed by the hyperkeratosis of the hyponychium which was considerably thickened. They seem to arise in the intercellular spaces. These structures coalesce and enlarge. They react like neutral and acid mucopolysaccharides. These clumps, previously described by Zaias in psoriasis of the nail, are also found in several cutaneous hyperkeratotic diseases. Their dermal origin has not been confirmed.