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EMISSIVE STEREOSCAN AND TRANSMISSION ELECTRON MICROSCOPE PROFILES OF THE STRATUM CORNEUM
Author(s) -
SIMS R. T.
Publication year - 1970
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1970.tb06836.x
Subject(s) - stratum corneum , electron microscope , transmission electron microscopy , epidermis (zoology) , corneocyte , biophysics , stratum , materials science , chemistry , pathology , anatomy , biology , optics , medicine , nanotechnology , physics , paleontology
Summary— A study by conventional electron microscopy of the black lesions in the dermatosis of kwashiorkor revealed no structural changes that could be associated with the colour change. The appearance of the epidermis was similar to that of depigmented skin. Intercellular spaces about 800 A wide between cornified cells could not be reconciled with the barrier function of the stratum corneum but this property could reside in retaining flanges over the edges of the cells. Scrutiny of the superficial surface of intact sheets and the cut surface of sections of healthy stratum corneum by the emissive mode of the Cambridge Scientific Instrument Company's Stereoscan showed that the intercellular space between cornified cells must be occupied by some structural component not demonstrated by transmission electron microscopy.