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SKIN ARGINASE ACTIVITY AS A MEASURE OF SKIN CHANGE UNDER THE INFLUENCE OF SOME ALKANES AND ALKENES *
Author(s) -
BROWN V. K. H.,
BOX VALERIE L.
Publication year - 1970
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1970.tb06102.x
Subject(s) - arginase , epidermis (zoology) , carbon chain , dermis , chemistry , guinea pig , biochemistry , organic chemistry , biology , endocrinology , anatomy , amino acid , arginine
SUMMARY.— Guinea‐pig epidermal soluble arginase has been shown to be increased by topical application of some linear and branched alkanes and alkenes and, although the response is related to the carbon chain size, the response does not always quantitatively reflect change in epidermis/dermis ratios. It is suggested that skin arginase activity will provide a measurable index of epidermal change due to non‐cyclic aliphatic hydrocarbons.