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HEREDITARY ANGIO‐OEDEMA TREATED WITH E‐AMINOCAPROIC ACID
Author(s) -
CHAMPION R. H.,
LACHMANN P. J.
Publication year - 1969
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1969.tb15938.x
Subject(s) - aminocaproic acid , epsilon aminocaproic acid , medicine , hereditary angioedema , complement (music) , gastroenterology , edema , anesthesia , surgery , pathology , immunology , chemistry , biochemistry , complementation , gene , phenotype
SUMMARY.— Two brothers with hereditary angio‐oedema have been studied, the only 2 cases among 227 patients with angio‐oedema seen in 10 years. The absence of the inhibitor of the activated first component of complement in their serum confirmed the diagnosis. In a double blind trial their symptoms were partially controlled by ε ‐ aminocaproic acid, although there were no consistent changes in the serum complement levels.