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THE DIURNAL MITOTIC RHYTHM IN THE HUMAN EPIDERMIS 1
Author(s) -
FISHER L. B.
Publication year - 1968
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1968.tb12263.x
Subject(s) - mitosis , rhythm , epidermis (zoology) , circadian rhythm , biology , medicine , anatomy , neuroscience , microbiology and biotechnology
SUMMARY. —A diurnal mitotic rhythm is found in the human epidermis varying from 0·1 to 0·9 mitoses per one thousand viable epidermal cells, with a peak at 1 a.m. Sustained exercise is shown to have a profound effect on mitosis, almost completely inhibiting it. From a consideration of this and other work it is suggested that the diurnal rhythm is due to variation in the level of the corticosteroid hormones, and that adrenalin produces an additional effect during exercise