Premium
The Hypertension in the Very Elderly Trial – latest data
Author(s) -
Mukhtar Omar,
Jackson Stephen H. D.
Publication year - 2013
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.2012.04427.x
Subject(s) - medicine , clinical trial , cohort , cohort study , gerontology , intensive care medicine
Early trials in the field of hypertension focused on adults in their fifties and sixties. However, with the passage of time, a progressive effort has been made to expand the evidence base for treatment in older adults. 2008 saw publication of data from the H ypertension in the V ery E lderly T rial which demonstrated significant mortality and morbidity benefits from antihypertensive therapy in octogenarians. More recently, additional data from this cohort has been published suggesting that appropriate anti‐hypertensive therapy may lead to a reduction in incident cognitive impairment and fractures, whilst a 1 year open label extension of the main study confirmed many of the original trial findings. This review provides an overview of the H ypertension in the V ery E lderly T rial whilst also discursively evaluating the latest data.