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Recent developments in the clinical pharmacology of classical cytotoxic chemotherapy
Author(s) -
Boddy Alan V.
Publication year - 2006
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.2006.02714.x
Subject(s) - pharmacogenetics , pharmacodynamics , pharmacology , medicine , clinical pharmacology , intensive care medicine , systems pharmacology , medical physics , pharmacokinetics , drug , biology , biochemistry , gene , genotype
Advances in analytical methods, imaging techniques and an increased understanding of the influence of pharmacogenetic factors have added to our knowledge of the pharmacology of many chemotherapeutic agents. Extending the use of these approaches to pharmacodynamic end‐points, together with the application of population‐based modelling techniques, offers the potential to develop truly individualized therapy in the future.