Premium
The implications of a growing evidence base for drug use in elderly patients. Part 3. β‐adrenoceptor blockers in heart failure and thrombolytics in acute myocardial infarction
Author(s) -
Mangoni A. A.,
Jackson S. H. D.
Publication year - 2006
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.2006.02611.x
Subject(s) - medicine , myocardial infarction , heart failure , drug , adrenergic beta antagonists , cardiology , intensive care medicine , pharmacology , propranolol
β‐adrenoceptor blockers and thrombolytic agents are of established value in the pharmacological management of heart failure and ST‐elevation myocardial infarction, respectively. However, there is uncertainty as to whether these therapeutic strategies can be safely and effectively adopted in elderly patients with comorbidities, particularly in old‐old individuals. This review focuses on these trials and the age‐related efficacy and safety of these drugs.