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Yohimbine increases human salivary secretion.
Author(s) -
Chatelut E.,
Rispail Y.,
Berlan M.,
Montastruc JL
Publication year - 1989
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1989.tb05440.x
Subject(s) - yohimbine , secretion , saliva , pharmacology , medicine , endocrinology , biology , receptor , antagonist
The effect of oral yohimbine (14 mg) on salivary secretion was evaluated in healthy volunteers. Yohimbine significantly increased salivary secretion when compared with placebo. This effect was significant from 60 min until 180 min after administration under our experimental conditions. Yohimbine (or alpha 2‐adrenoceptor blocking agents) could have a potential interest in the treatment of dry mouths.