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Effect of short‐acting nitroglycerin on heart rate: evaluation by a self‐monitoring device.
Author(s) -
Lahtela JT,
Sotaniemi EA
Publication year - 1989
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1989.tb03549.x
Subject(s) - nitroglycerin (drug) , medicine , heart rate , ischaemic heart disease , anesthesia , sublingual administration , cardiology , blood pressure
The efficacy of two sublingual nitroglycerin formulations was compared in 10 healthy subjects and 10 patients with ischaemic heart disease. A new microcomputerized device was used to record and analyze heart rate. The rise in heart rate began 1‐1.5 min after administration of nitroglycerin tablets and was maximal within 3 min. The effect was more rapid with a quickly dissolving compound. The recording equipment was reliable, simple to use and inexpensive.