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The effect of phentolamine on basal and pethidine‐induced inhibition of gastric emptying in healthy volunteers.
Author(s) -
Petring OU
Publication year - 1989
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1989.tb03520.x
Subject(s) - phentolamine , pethidine , gastric emptying , basal (medicine) , volunteer , medicine , stomach , pharmacology , chemistry , anesthesia , endocrinology , stimulation , analgesic , biology , insulin , agronomy
1. The effect of phentolamine 5 mg i.v. on basal and pethidine‐induced inhibition of gastric emptying of semisolid TC‐99m labelled Chelex‐100 resin/oatmeal was studied in ten healthy volunteers. 2. Each volunteer acted as his/her own control. 3. Basal gastric emptying remained unchanged after administration of phentolamine. 4. Administration of phentolamine reversed the pethidine‐induced inhibition of gastric emptying.