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Effect of cicloprolol in intraocular pressure in healthy volunteers.
Author(s) -
Mekki QA,
Turner P
Publication year - 1988
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1988.tb03368.x
Subject(s) - heart rate , intraocular pressure , blood pressure , medicine , placebo , partial agonist , agonist , anesthesia , ophthalmology , receptor , alternative medicine , pathology
Two oral doses of cicloprolol (50 mg and 100 mg), a beta 1‐adrenoceptor partial agonist, were administered to nine healthy volunteers in a double‐blind placebo‐controlled study. Intraocular pressure (IOP) and exercise heart rate were reduced while the resting heart rate and blood pressure remained unchanged. The responses to the two different doses of cicloprolol were similar.