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Comparison of the effects of dopamine, dobutamine, and dopexamine upon renal blood flow: a study in normal healthy volunteers.
Author(s) -
Mousdale S,
Clyburn PA,
Mackie AM,
Groves ND,
Rosen M
Publication year - 1988
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1988.tb03345.x
Subject(s) - blood pressure , dobutamine , dopamine , crossover study , medicine , renal blood flow , heart rate , blood flow , anesthesia , hemodynamics , cardiology , placebo , pathology , alternative medicine
1. We compared the effects of dopexamine, dopamine and dobutamine on the heart rate, blood pressure and renal blood flow of six healthy volunteers in an open triple crossover trial. 2. The results suggest that at the dose ranges investigated dopamine was the most effective agent for increasing renal blood flow.