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Intravenous bumetanide attenuates the rise in plasma vasopressin concentrations during major surgical operations.
Author(s) -
Kaufman L,
Bailey PM
Publication year - 1987
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1987.tb03036.x
Subject(s) - bumetanide , vasopressin , medicine , plasma concentration , anesthesia , endocrine system , plasma levels , pharmacology , endocrinology , hormone , chemistry , sodium , cotransporter , organic chemistry
During a study in seven patients on the endocrine response to major surgical procedures under general anaesthesia an incidental finding was that the administration of intravenous bumetanide prior to surgical stimulation led to reduced concentrations of plasma vasopressin (AVP) when compared with a control group of patients.