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Benoxaprofen‐adverse reactions and monitoring in general practice.
Author(s) -
Newrick PG,
Bainton D
Publication year - 1987
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1987.tb03029.x
Subject(s) - medicine , general practice , adverse effect , medical prescription , drug reaction , osteoarthritis , extended release , drug , clinical practice , alternative medicine , physical therapy , pharmacology , family medicine , pathology
We report on the pattern of use of benoxaprofen (Opren) in a single group practice for a period which included the complete clinical life of the drug. One hundred and seventy‐two patients of the 6495 practice patients had been prescribed benoxaprofen, but 55% had only a small exposure (less than 20 g). Recorded adverse reactions, of which none was serious, appeared in 25 patients. Most were taking benoxaprofen for osteoarthritis (53%) or non‐specific musculoskeletal pain (39.9%). The issue of a prescription was not recorded in 19.6% of cases and 88% were on additional drugs. Greater precision in record‐keeping is required to avoid problems similar to the experience with benoxaprofen.