Premium
Differential effects of atenolol and enalapril on memory during treatment for essential hypertension.
Author(s) -
Lichter I.,
Richardson PJ,
Wyke MA
Publication year - 1986
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1986.tb05228.x
Subject(s) - atenolol , enalapril , essential hypertension , placebo , medicine , ace inhibitor , angiotensin converting enzyme , randomized controlled trial , pharmacology , anesthesia , cardiology , blood pressure , alternative medicine , pathology
A randomized single‐blind study was designed to compare the performance on memory tests requiring recall of information relevant to everyday life of two groups of hypertensive patients. One group of 13 patients were taking a beta‐adrenoceptor blocker (atenolol) and the other group of 12 patients received the angiotensin‐converting enzyme inhibitor (enalapril). The results suggested that when compared with placebo the group of patients treated with enalapril showed no changes in memory function, whilst there was a mild, but consistent deficit in the group taking atenolol.