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No effects on sleep of a histamine H1‐receptor antagonist: temelastine.
Author(s) -
Adam K,
Oswald I
Publication year - 1986
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1986.tb02963.x
Subject(s) - antagonist , histamine , pharmacology , histamine h1 receptor , medicine , sleep (system call) , receptor antagonist , histamine h2 receptor , histamine h1 antagonists , receptor , endocrinology , computer science , operating system
Twelve volunteer poor sleepers of mean age 57 years took placebo on each of 3 consecutive nights, and temelastine 100 mg on 3 consecutive nights in a double‐blind balanced order study. Sleep in the EEG laboratory was unaffected by the drug.