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Mianserin, maprotiline and the electroencephalogram.
Author(s) -
Sedgwick EM,
Edwards JG
Publication year - 1983
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1983.tb05873.x
Subject(s) - maprotiline , mianserin , electroencephalography , placebo , anesthesia , medicine , psychology , psychiatry , antidepressant , anxiety , alternative medicine , pathology
1 EEGs were recorded from patients with depressive illness before and after four weeks of treatment with mianserin, maprotiline or placebo. 2 Visual analysis of the records showed a small but statistically significant increase in frequency of beta activity in the mianserin group. 3 One subject taking maprotiline developed spike and wave discharges but had no convulsive seizures. 4 The findings do not support those of previous studies. It seems that changes seen in the EEG early after treatment are not sustained for four weeks.