Premium
A comparison of a combination of penbutolol and frusemide with the two compounds individually in the treatment of hypertension.
Author(s) -
Chadha DR,
Houtzagers JJ
Publication year - 1983
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1983.tb02217.x
Subject(s) - medicine , furosemide , blood pressure , essential hypertension , randomized controlled trial , pharmacology , cardiology
Forty‐one patients completed a randomized, double‐blind, between‐group comparison of a combination of penbutolol and frusemide, with penbutolol alone, and frusemide alone in the management of mild to moderate essential hypertension. The results suggest that the combination caused a superior reduction in systolic and diastolic pressure compared with penbutolol and a superior reduction in systolic blood pressure compared with frusemide.