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The effect of glucagon on the swallowing of capsules.
Author(s) -
Channer KS,
Bolton R,
AlHilli S,
Nakielny R,
Virjee JP
Publication year - 1983
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1983.tb02197.x
Subject(s) - supine position , swallowing , glucagon , peristalsis , medicine , motility , endocrinology , gastroenterology , anesthesia , surgery , hormone , biology , genetics
Glucagon (0.3 mg) given intravenously to 45 patients with normal oesophageal motility significantly reduced oesophageal transit of hard gelatin capsules when swallowed in the supine position with 15 ml water, compared to an age/sex matched group. This is taken to represent an effect on oesophageal peristalsis which has not previously been recognised.