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A method for monitoring drug effects on male sexual response: the effect of single dose labetalol.
Author(s) -
Riley AJ,
Riley EJ,
Davies HJ
Publication year - 1982
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1982.tb04959.x
Subject(s) - labetalol , ejaculation , medicine , placebo , sexual stimulation , anesthesia , pharmacology , blood pressure , alternative medicine , pathology
1 A method for monitoring the effect of drugs on the genital response to stimulation provided by vibration is described. 2 Using this method, the effect on male sexual response of two oral doses (100 mg and 300 mg) labetalol were studied and compared with placebo in six subjects. 3 Labetalol did not affect the attainment or maintenance of erection. 4 Labetalol delayed ejaculation in a dose‐related manner. 5 Labetalol treatment resulted in a significant dose‐related delay in detumescence.