Premium
Tooth pulp stimulation: a method of determining the analgesic efficacy of meptazinol in man.
Author(s) -
Gabka J.,
Price RK
Publication year - 1982
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1982.tb04943.x
Subject(s) - analgesic , placebo , anesthesia , medicine , analgesic agents , stimulation , pharmacology , alternative medicine , pathology
A dose‐ranging study of meptazinol was carried out using the pain threshold to electrical tooth pulp stimulation in healthy volunteers as the pain model. A well defined dose‐response curve was found for oral meptazinol (50 mg, 100 mg, 150 mg and 200 mg) and placebo. The methodology and results are discussed in terms of subsequent clinical experience with meptazinol.