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The effects of ampicillin oral contraceptive steroids in women.
Author(s) -
Back DJ,
Breckenridge AM,
MacIver M.,
Orme M.,
Rowe PH,
Staiger C.,
Thomas E.,
Tjia J.
Publication year - 1982
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1982.tb04932.x
Subject(s) - ampicillin , medicine , levonorgestrel , menstrual cycle , regimen , estrogen , population , hormone , endocrinology , physiology , family planning , antibiotics , research methodology , chemistry , biochemistry , environmental health
1 Thirteen women taking long term oral contraceptive steroids were studied while taking ampicillin (500 mg three times daily) and compared to a control cycle while not taking ampicillin. 2 There were no significant changes in the plasma concentrations of ethinyloestradiol, levonorgestrel, follicle stimulating hormone or progesterone, although lower concentrations of ethinyloestradiol were noted in two women. 3 We conclude that most patients taking oral contraceptive steroids do not need to take alternative contraceptive precautions while taking ampicillin.