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The effect of co‐trimoxazole on serum creatinine.
Author(s) -
Dijkmans BA,
Hooff JP,
Wolff FA,
Mattie H
Publication year - 1981
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1981.tb01293.x
Subject(s) - creatinine , renal function , trimethoprim , medicine , sulfamethoxazole , urology , endocrinology , chemistry , antibiotics , biochemistry
1 Co‐trimoxazole induces a highly significant and reversible elevation of the serum creatinine level. 2 In renal‐allograft patients the degree of this elevation is significantly correlated with the concentration of serum creatinine before administration of co‐trimoxazole and with the concentration of non‐protein‐bound trimethoprim.