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Pharmacological and clinical importance of narcotic antagonists and mixed antagonists‐use in cardiology.
Author(s) -
Coltart DJ,
Malcolm AD
Publication year - 1979
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1979.tb04705.x
Subject(s) - pentazocine , pethidine , buprenorphine , medicine , analgesic , anesthesia , morphine , narcotic , hemodynamics , opioid , antagonist , sympatholytic , clinical pharmacology , pharmacology , blood pressure , receptor
1 The treatment of pain of cardiac origin requires a knowledge of the haemodynamic action of the analgesic agents used. 2 The haemodynamic effects of morphine, diamorphine, pavaveretum, pethidine and pentazocine are reviewed. 3 Clinical experience with the new antagonist analgesic buprenorphine is reported. 4 These studies indicate that buprenorphine may be the agent of choice for the relief of severe pain in patients with unstable circulation.