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Effect of treatment of hypertension in the primary preventive trial, Goteborg, Sweden.
Author(s) -
Wilhelmsen L,
Berglund G,
Sannerstedt R,
Hansson L,
Andersson O,
Sievertsson R,
Wikstrand J
Publication year - 1979
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1979.tb04699.x
Subject(s) - medicine , primary (astronomy) , intensive care medicine , pharmacology , physics , astronomy
1 A treatment group comprising 635 hypertensive men (casual SBP greater than 175 or DBP greater than 115 twice) was compared with a reference group (n = 391 men; casual SBP greater than 175 or DBP greater than 115 only at screening). All men belonged to the same population sample of 7,455 men aged 47‐54 yr. 2 The two groups did not differ with respect to age, smoking habits or cholesterol values, but screening BPs were higher in the treatment group. 3 During 4.3 years' follow‐up there was a significantly lower total death rate in the treatment group compared with reference group. 4 There was also a strong tendency towards lower incidence of non‐fatal myocardial infarction (P = 0.06). The pooled incidence of non‐fatal myocardial infarction and fatal CHD was lower in the treatment group than in the reference group (P less than 0.03).