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Environmental factors affecting antipyrine metabolism in London factory and office workers.
Author(s) -
Fraser HS,
Mucklow JC,
Bulpitt CJ,
Kahn C,
Mould G,
Dollery CT
Publication year - 1979
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1979.tb00928.x
Subject(s) - office workers , medicine , saliva , factory (object oriented programming) , physiology , operations management , economics , computer science , programming language
1 Measurements of antipyrine clearance in saliva have been made in 128 London factory and office workers. 2 Mean antipyrine clearance in 56 Asian immigrants was 40% slower than in 72 White subjects. 3 Although dietary differences existed between the two groups, analysis of their effect independently of race was impossible since all but one of the vegetarians were Asian and the non‐vegetarians were nearly all White. 4 In the White subjects, use of the oral contraceptive reduced clearance by 38% in women, while cigarette smoking increase clearance by 38% in men.